ppt Acute and Chronic Inflammation

The inflammatory response consists of two main components :

  • a vascular reaction
  • a cellular reaction

   à many tissues and cells are involved in

        these reactions, including the fluid and

        proteins of plasma, circulating cells,

        blood vessels, and cellular and

        extracellular constituents of connective tissue

The components of acute and chronic inflammatory responses: circulating cells and proteins, cells of blood vessels, and cells and proteins of the extracellular matrix

Inflammation is divided into :

  • Acute inflammation is rapid in onset (seconds or minutes) and is of relatively short duration, lasting for minutes, several hours, or a few days; its main characteristics are the exudation of fluid and plasma proteins (edema) and the emigration of leukocytes, predominantly neutrophils.
  • Chronic inflammation is of longer duration and is associated histologically with the presence of lymphocytes and macrophages, the proliferation of blood vessels, fibrosis, and tissue necrosis.

Definition of acute inflammation :

a rapid response to an injurious agent that serves to deliver mediators of host defense-leukocytes and plasma proteins-to the site of injury

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