Antibacterial Activity of Secondary Metabolite Compounds From Leaf of Eclipta alba L. Hassk

1Hasballah Kartini, 2Murniana, and 2Nurdin Saidi

1Department of Pharmacology, Faculty of Medicine, Syiah Kuala University, Banda Aceh 23111, Indonesia;2Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala University,  Banda Aceh 23111, Indonesia. Corresponding Author: kartinirusly@gmail.com

Abstract

 Two secondary metabolite compounds of steroid and triterpenoid derivates had been extracted from the leaf of Eclipta alba L. Hassk. The extraction of the compounds was carried out by maceration and then isolated by column chromatography. Structural elucidation was established using GC-MS. Both of the compounds showed antibacterial activity against S. mutans, A. viscosus, and L. kaesal at the concentration of 5%, 10%, and 25%.

Keywords:Eclipta alba L. Hassk, antibacterial activity, steroid and triterpenoid derívates.

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